I have had this odd behavior over the last couple of months, and it's random. I will open certain Reason files, some old, some new. And even though they saved fine and sounded good, when I reopen them, some of the instruments will be out of tune, sometimes it a little bit, sometimes it's quite a bit. Not only does this happen to midi instruments but to wav files as well. When I open the wav file in the pitch edit mode, it's right on the money. No chorus or flange pulling it out of tune. Anyone else come across this?

Thanks in advance.